Lung Cancer

Lung cancer at a glance

Lung cancer is the most common cancer in the world with over 1.61 million people diagnosed with the disease every year. The U.S., Europe and Japan account for almost 43% of all new cases.
Lung cancer represents the most common cause of death from cancer, with 1.38 million deaths (18.2% of the total) [1] Improving survival in lung cancer is a major challenge for modern oncology considering that 5-year survival remains lower than 15% across all stages of disease.[2]

Classification:

  • Small Cell Lung Cancer (SCLC) (13%) [3]
  • Non-Small Cell Lung Cancer (NSCLC) (87%) [3]
    • Non-squamous cell carcinoma:
      • Adenocarcinoma (35-40%) [4]
      • Other cell types
    • Large cell carcinoma (LCC) (10-15%) [4]
    • Squamous cell carcinoma (SCC) or epidermoid (25-30%) [4]
    • Mixed tumors (3-4%)[5]

Bibliography

  • 1. Globocan 2008, International Agency for Research on Cancer (IARC), World Health Organization
  • 2. L. Crinò et al. Early stage and locally advanced (non-metastatic) non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol (2010) 21 (suppl 5): v103-v115
  • 3. National Cancer Institute (www.cancer.gov)
  • 4. Syed Huq et al, Non-small cell lung cancer, 2010
  • 5. Benjamin Movsas, MD et al, Non-small cell lung cancer, 2011

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